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1-(Chloromethyl)-4-Aza-1-Azonia Bicyclo[2.2.2]Octane Chloride CAS NO 36273-11-7


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CAS No.:36273-11-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-(Chloromethyl)-4-Aza-1-Azonia Bicyclo[2.2.2]Octane Chloride is a versatile quaternary ammonium salt derivative of DABCO (1,4-diazabicyclo[2.2.2]octane), serving as a key reactive intermediate and functional building block. Its value lies in its ability to introduce cationic and reactive chloromethyl functionalities into target molecules, enabling advanced material synthesis and modification. This compound is essential for researchers and manufacturers in the pharmaceutical, polymer, and specialty chemical industries seeking to develop catalysts, antimicrobial agents, or functional polymers.

Application

  • Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring quaternary ammonium or bicyclic amine moieties for enhanced bioavailability or activity.
  • Polymer Chemistry & Material Science: Acts as a monomer or cross-linking agent for creating cationic polymers, ion-exchange resins, and functional coatings with tailored surface properties.
  • Phase Transfer Catalyst (PTC) Precursor: Serves as a starting material for synthesizing advanced, structurally defined phase transfer catalysts used in organic synthesis.
  • Antimicrobial Agent Synthesis: A key precursor for developing novel quaternary ammonium compounds (QACs) with potent biocidal properties for disinfectants and preservatives.
  • Surface Modification Agent: Employed to impart a permanent positive charge or reactive sites onto surfaces of fibers, plastics, or silica for specialized applications.
  • Research & Development: A valuable reagent in academic and industrial R&D for exploring new reactions in organic and medicinal chemistry.

Basic Information

Product Name 1-(Chloromethyl)-4-Aza-1-Azonia Bicyclo[2.2.2]Octane Chloride
CAS No. 36273-11-7
Molecular Formula C7H14Cl2N2
Molecular Weight 197.11 g/mol
Synonyms 1-(Chloromethyl)-1-azonia-4-azabicyclo[2.2.2]octane chloride; DABCO Chloromethyl Chloride; 1-Chloromethyl-4-aza-1-azoniabicyclo[2.2.2]octane chloride; 4-Aza-1-azoniabicyclo[2.2.2]octane, 1-(chloromethyl)-, chloride; 1-(Chloromethyl)-1,4-diazoniabicyclo[2.2.2]octane dichloride; Quaternized DABCO Chloride; DABCO-CM Chloride
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Quality Control

Our 1-(Chloromethyl)-4-Aza-1-Azonia Bicyclo[2.2.2]Octane Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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