Description

tert-Butyl (Mesitylsulfonyl)Oxycarbamate is a specialized organic intermediate featuring a protected carbamate group activated by a mesitylsulfonyl leaving group. This compound matters for its role as a key building block in sophisticated organic synthesis, particularly in the development of pharmaceuticals and advanced materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing carbamate or urea functionalities.
• Peptide Mimetics & PROTACs: Utilized in the construction of peptide backbones and as a linker component in Proteolysis Targeting Chimeras (PROTACs) for targeted protein degradation.
• Agrochemical Synthesis: Acts as an intermediate in the production of novel herbicides, fungicides, and insecticides that require controlled release or specific targeting mechanisms.
• Polymer Modification: Employed to introduce functional carbamate groups into polymer chains, modifying material properties for specialty coatings or adhesives.
• Cross-Coupling Reactions: Functions as a substrate in palladium-catalyzed cross-coupling reactions to form new carbon-nitrogen or carbon-carbon bonds.
• Chemical Biology Probes: Used in the design and synthesis of molecular probes for studying enzyme activity and biological pathways.

Basic Information

Product Name	tert-Butyl (Mesitylsulfonyl)Oxycarbamate
CAS No.	36016-39-4
Molecular Formula	C14H21NO5S
Molecular Weight	315.39 g/mol
Synonyms	tert-Butyl N-[(2,4,6-trimethylphenyl)sulfonyl]oxycarbamate; BOC-ON (Mesitylene Sulfonate); tert-Butyloxycarbonyloxy-2,4,6-trimethylbenzenesulfonate; (tert-Butoxycarbonyloxy)(mesitylsulfonyl)amide; BOC-ON (Mesylate); N-(tert-Butoxycarbonyloxy)-2,4,6-trimethylbenzenesulfonamide; Mesitylsulfonyl BOC-ON; 2,4,6-Trimethylbenzenesulfonic acid tert-butoxycarbonyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl (Mesitylsulfonyl)Oxycarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.