Description

2-Iodo-5-Methyl-Phenol is a halogenated phenolic compound that serves as a versatile and critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both an iodine substituent and a phenolic hydroxyl group, makes it a valuable building block for constructing complex molecules with tailored properties. This high-purity intermediate is essential for research and development in the pharmaceutical and agrochemical sectors, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for thyroid hormone analogs and other iodine-containing therapeutic agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators, leveraging the phenolic and halogen functionalities.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials due to its ability to modify electronic properties.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing specialized iodinated dyes and colorants.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for constructing biaryl systems.

Basic Information

Product Name	2-Iodo-5-Methyl-Phenol
CAS No.	35928-80-4
Molecular Formula	C7H7IO
Molecular Weight	234.04 g/mol
Synonyms	5-Methyl-2-iodophenol; 2-Hydroxy-4-methyl-1-iodobenzene; 4-Methyl-2-iodophenol; 2-Iodo-p-cresol; o-Iodo-p-cresol; 1-Iodo-2-hydroxy-4-methylbenzene; Phenol, 2-iodo-5-methyl-
EINECS	Contact for details

Quality Control

Our 2-Iodo-5-Methyl-Phenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring consistency and reliability for our global B2B partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.