Description

4,6-Dichloro-3-Pyridazinecarbonitrile is a versatile heterocyclic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring reactive chloro and cyano substituents, makes it a critical intermediate for constructing complex nitrogen-containing compounds. This high-value intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the pyridazine core for bioactivity.
• Material Science Research: Serves as a building block for creating specialized polymers, ligands for catalysis, and organic electronic materials.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes, enzyme inhibitors, and activity-based protein profiling (ABPP) reagents.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	4,6-Dichloro-3-Pyridazinecarbonitrile
CAS No.	35857-90-0
Molecular Formula	C5HCl2N3
Molecular Weight	173.99 g/mol
Synonyms	3-Cyano-4,6-dichloropyridazine; 4,6-Dichloropyridazine-3-carbonitrile; 4,6-Dichloro-3-cyanopyridazine; 4,6-Dichloro-3-pyridazinecarbonitrile; 35857-90-0; 4,6-Dichloro-3-pyridazinecarbonitrile; 4,6-Dichloro-3-cyano-pyridazine
EINECS	Contact for details

Quality Control

Our 4,6-Dichloro-3-Pyridazinecarbonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity, purity, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP standards for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.