Description

(Diisopropoxyphosphoryl)Methyl 4-Methylbenzenesulfonate is a specialized organophosphorus sulfonate ester, a high-value intermediate in advanced organic synthesis. This compound matters for its role as a key phosphorylating and sulfonylating agent, enabling precise molecular modifications critical for developing complex chemical architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or requiring phosphate prodrug strategies.
• Agrochemical Synthesis: Used in the production of advanced herbicides, insecticides, and plant growth regulators that incorporate phosphonate or sulfonate functionalities.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized phosphine-phosphonate or sulfonate-containing ligands for transition metal catalysis.
• Polymer Modification: Employed to introduce functional phosphate or sulfonate groups into polymer backbones, altering properties like solubility, adhesion, or flame retardancy.
• Material Science Research: Utilized in surface functionalization and the creation of self-assembled monolayers (SAMs) for sensors and electronic materials.
• Chemical Biology Probes: Acts as a reagent for labeling or modifying biomolecules to study biological pathways and protein functions.

Basic Information

Product Name	(Diisopropoxyphosphoryl)Methyl 4-Methylbenzenesulfonate
CAS No.	35717-98-7
Molecular Formula	C14H23O6PS
Molecular Weight	350.36 g/mol
Synonyms	p-Toluenesulfonic Acid (Diisopropoxyphosphoryl)Methyl Ester; [(4-Methylphenyl)sulfonyl]methyl Diisopropyl Phosphite; Diisopropyl [(Tosyloxy)methyl]phosphonate; (Tosyloxymethyl)phosphonic Acid Diisopropyl Ester; Phosphonic Acid, P-[(4-Methylbenzenesulfonyl)oxy]methyl]-, Diisopropyl Ester; Diisopropyl (Tosyloxymethyl)phosphonate
EINECS	Contact for details

Quality Control

Our (Diisopropoxyphosphoryl)Methyl 4-Methylbenzenesulfonate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy. We ensure compliance with relevant industry standards for fine chemical intermediates. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.