Description

(o-Pivaloylhydroxyl)Amine is a specialized organic compound featuring a hydroxylamine moiety protected by a pivaloyl group. This structure makes it a valuable building block and reagent in advanced organic synthesis, particularly for the controlled introduction of hydroxylamine functionality. It is primarily utilized by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those requiring hydroxylamine or N-O containing pharmacophores.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators.
• Chemical Research Reagent: Employed in academic and industrial R&D for method development, catalysis studies, and the construction of complex molecular architectures.
• Polymer Chemistry: Serves as a functional monomer or modifier in the synthesis of specialty polymers with tailored properties.
• Cross-coupling Reactions: Acts as a coupling partner in metal-catalyzed reactions for C-N bond formation.
• Protecting Group Strategy: The pivaloyl group offers steric protection, making this compound useful in multi-step synthetic sequences where selective deprotection is required.

Basic Information

Item	Details
Product Name	(o-Pivaloylhydroxyl)Amine
CAS No.	35657-34-2
Molecular Formula	C5H11NO2
Molecular Weight	117.15 g/mol
Synonyms	O-Pivaloylhydroxylamine; Pivaloyl Hydroxylamine; 2,2-Dimethylpropanoic acid, N-hydroxyamide; N-Hydroxypivalamide; N-Hydroxy-2,2-dimethylpropanamide; tert-Butylcarbonylhydroxylamine; PivONH2
EINECS	Contact for details

Quality Control

Our (o-Pivaloylhydroxyl)Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	95 - 100 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.