Description

Ethyl 3-Hydroxybutyrate is a valuable chiral building block and ester derivative of 3-hydroxybutyric acid. This compound is significant for its role as a key intermediate in the synthesis of complex pharmaceuticals, fine chemicals, and flavor & fragrance ingredients. It is primarily needed by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical sectors seeking high-purity intermediates for asymmetric synthesis.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the production of active pharmaceutical ingredients (APIs), particularly in routes involving β-hydroxy ester motifs.
• Flavor and Fragrance Ingredient: Used in the synthesis of esters that contribute fruity and buttery notes to food flavors and perfumery compositions.
• Agrochemical Synthesis: Serves as a building block for creating advanced pesticides and herbicides with specific stereochemical requirements.
• Polymer Chemistry: Acts as a monomer or co-monomer precursor for synthesizing specialized biodegradable polyesters.
• Organic Synthesis Reagent: Employed in various organic transformations, including aldol reactions and nucleophilic additions, as a source of a protected hydroxy group.
• Biochemical Research: Used in studies related to ketone bodies and metabolic pathways as an analog or precursor.

Basic Information

Product Name	Ethyl 3-Hydroxybutyrate
CAS No.	35608-64-1
Molecular Formula	C6H12O3
Molecular Weight	132.16 g/mol
Synonyms	Ethyl 3-hydroxybutanoate; 3-Hydroxybutyric Acid Ethyl Ester; Ethyl β-Hydroxybutyrate; Ethyl DL-3-Hydroxybutyrate; Ethyl (±)-3-Hydroxybutyrate; Butanoic acid, 3-hydroxy-, ethyl ester; β-Hydroxybutyric acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 3-Hydroxybutyrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider holding under an inert atmosphere to maintain optimal quality.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC/HPLC)	≥ 98.0%
Optical Purity (Chiral GC/HPLC)	Contact for details
Specific Rotation (if applicable)	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.