Description

3-Chloro-4-Hydroxy-5-Methyl-Benzoic Acid is a versatile halogenated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for creating complex molecules with specific biological or material properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for anti-inflammatory and antimicrobial agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators due to its bioactive scaffold.
• Liquid Crystal & OLED Materials: Serves as a building block for creating specialized aromatic cores in electronic display and lighting materials.
• Polymer Modification: Employed to introduce functional groups into polymer chains, enhancing properties like adhesion, solubility, or thermal stability.
• Dyestuff & Pigment Intermediate: Utilized in the production of high-performance dyes and organic pigments for industrial applications.
• Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	3-Chloro-4-Hydroxy-5-Methyl-Benzoic Acid
CAS No.	35458-34-5
Molecular Formula	C8H7ClO3
Molecular Weight	186.59 g/mol
Synonyms	5-Methyl-3-chloro-4-hydroxybenzoic acid; 4-Hydroxy-3-chloro-5-methylbenzoic acid; 3-Chloro-4-hydroxy-5-methylbenzoic acid; Benzoic acid, 3-chloro-4-hydroxy-5-methyl-; 3-Chloro-5-methylsalicylic acid; 3-Chloro-4-hydroxy-m-toluic acid
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-4-Hydroxy-5-Methyl-Benzoic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting key parameters such as assay, impurity profile, and physical characteristics. Our quality systems are designed to meet the rigorous demands of GMP and ISO standards for intermediate manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.