Description

Carbobenzyloxycarboxylic Acid is a key protected amino acid derivative widely used as a versatile building block in organic synthesis. Its primary value lies in its role as a crucial reagent for the introduction and protection of the carbobenzyloxy (Cbz) group, a fundamental strategy in peptide chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for the synthesis of peptides, active pharmaceutical ingredients (APIs), and other complex organic molecules where selective amine protection is required.

Application

• Peptide Synthesis: As a fundamental reagent for the introduction of the Cbz (carbobenzyloxy) protecting group onto amine functionalities during solid-phase and solution-phase peptide synthesis.
• Pharmaceutical Intermediates: Serves as a critical building block in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Organic Synthesis: Used as a versatile synthon for constructing amide bonds and protecting amines in the preparation of various fine chemicals and specialty compounds.
• Bioconjugation: Employed in the modification of biomolecules, where controlled amine coupling is necessary for creating labeled proteins or diagnostic reagents.
• Research & Development: A staple reagent in R&D laboratories for method development and the exploration of new synthetic pathways in medicinal chemistry.

Basic Information

Product Name	Carbobenzyloxycarboxylic Acid
CAS No.	35448-14-7
Molecular Formula	C9H9NO4
Molecular Weight	195.17 g/mol
Synonyms	Cbz-Gly-OH; N-Carbobenzyloxyglycine; N-(Benzyloxycarbonyl)glycine; Glycine, N-[(phenylmethoxy)carbonyl]-; Z-Gly-OH; Benzyloxycarbonylglycine; NSC 3349; N-Cbz-glycine
EINECS	Contact for details

Quality Control

Our Carbobenzyloxycarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment ensures batch-to-batch consistency and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	118°C - 122°C
Loss on Drying	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.