Description

(5S)-5-[(R)-1-Hydroxy-1,5-Dimethyl-4-Hexenyl]-2-Methyl-2-Cyclohexen-1-One is a high-purity chiral intermediate of significant commercial interest in the fine chemical and pharmaceutical sectors. Its complex stereochemistry makes it a valuable building block for the synthesis of advanced bioactive molecules. This compound is primarily sought by R&D laboratories and production facilities specializing in the development of fragrances, flavors, and active pharmaceutical ingredients (APIs).

Application

• Fragrance & Flavor Synthesis: A key chiral intermediate for creating sophisticated, high-value aroma chemicals and flavoring agents.
• Pharmaceutical Intermediates: Used in the research and production of complex drug molecules, particularly those requiring specific stereochemical configurations.
• Organic Synthesis Research: Serves as a versatile chiral synthon in academic and industrial research for developing novel organic compounds.
• Agrochemical Development: Potential application as a precursor in the synthesis of chiral active ingredients for crop protection products.
• Fine Chemical Manufacturing: Employed in the production of specialty chemicals where precise stereochemistry is critical for performance.

Basic Information

Product Name	(5S)-5-[(R)-1-Hydroxy-1,5-Dimethyl-4-Hexenyl]-2-Methyl-2-Cyclohexen-1-One
CAS No.	35346-20-4
Molecular Formula	C15H24O2
Molecular Weight	236.35 g/mol
Synonyms	(-)-Nootkatone; (4R,5S)-Nootkatone; (5S)-5-[(1R)-1-Hydroxy-1,5-dimethyl-4-hexen-1-yl]-2-methyl-2-cyclohexen-1-one; (5S,1'R)-Nootkatone; 5,6-Dihydro-7-isopropenyl-4,4,7-trimethyl-2(4H)-benzofuranone (related structure); Valencene derivative; Grapefruit ketone
EINECS	Contact for details

Quality Control

Our (5S)-5-[(R)-1-Hydroxy-1,5-Dimethyl-4-Hexenyl]-2-Methyl-2-Cyclohexen-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC and GC, to ensure it meets the high standards required for research and synthesis applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent oxidation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.