Description

6-Iodo-4-Oxo-4H-Chromene-2-Carboxylic Acid is a versatile and highly functionalized chromene derivative that serves as a critical synthetic intermediate. Its value lies in the strategic placement of iodine and carboxylic acid functional groups, enabling precise chemical modifications for advanced material and pharmaceutical synthesis. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to build complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other biologically active chromene-based molecules.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and plant growth regulators that leverage the chromene scaffold.
• Organic Synthesis Reagent: Serves as a versatile precursor for cross-coupling reactions (e.g., Suzuki, Sonogashira) due to the reactive iodine substituent, facilitating the construction of complex organic structures.
• Material Science Precursor: Employed in the development of organic electronic materials, dyes, and fluorescent markers due to the conjugated chromene core.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying enzyme activity and biological pathways.

Basic Information

Product Name	6-Iodo-4-Oxo-4H-Chromene-2-Carboxylic Acid
CAS No.	35204-43-4
Molecular Formula	C10H5IO4
Molecular Weight	316.05 g/mol
Synonyms	6-Iodo-4-oxo-4H-1-benzopyran-2-carboxylic acid; 6-Iodochromone-2-carboxylic acid; 2-Carboxy-6-iodo-4-chromone; 6-Iodo-4-oxochromene-2-carboxylic acid; 6-Iodo-2-carboxychromone; 4-Oxo-6-iodo-4H-chromene-2-carboxylic acid; 35204-43-4
EINECS	Contact for details

Quality Control

Our 6-Iodo-4-Oxo-4H-Chromene-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and stored in a dark location to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.