Description

Diosmetin 7-o-β-D-Glucuronide is a specific flavonoid glucuronide, a key metabolite of the natural flavone diosmetin. This compound is of significant interest for its role in pharmacokinetic and metabolic studies, serving as a crucial reference standard. It is primarily utilized by research institutions, pharmaceutical developers, and analytical laboratories focused on flavonoid metabolism, bioavailability, and the development of nutraceutical or pharmaceutical products.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified standard for quantitative and qualitative analysis in drug metabolism and pharmacokinetic (DMPK) studies.
• Metabolite Identification & Research: Essential for identifying and quantifying diosmetin metabolites in biological samples (plasma, urine) during preclinical and clinical research.
• Analytical Method Development: Serves as a critical component for developing and validating HPLC, LC-MS, and other chromatographic methods for flavonoid analysis.
• Nutraceutical & Cosmetic Research: Employed in studies investigating the bioavailability, stability, and efficacy of diosmetin-containing supplements and cosmetic formulations.
• Biochemical Research: Used in enzymatic studies related to glucuronidation pathways and phase II metabolism.

Basic Information

Product Name	Diosmetin 7-o-β-D-Glucuronide
CAS No.	35110-20-4
Molecular Formula	C22H20O12
Molecular Weight	476.39 g/mol
Synonyms	Diosmetin 7-O-β-D-Glucuronide; Diosmetin 7-Glucuronide; 7-O-β-D-Glucopyranuronosyl-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one; Luteolin 7-O-β-D-glucuronide 4'-methyl ether; 3',5,7-Trihydroxy-4'-methoxyflavone 7-glucuronide
EINECS	Contact for details

Quality Control

Our Diosmetin 7-o-β-D-Glucuronide is produced and tested under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, MS), to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95.0%
Water Content (KF)	≤5.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.