Description

2-O,3-O:5-O,6-o-Diisopropylidene-D-Mannose Oxime is a high-purity, protected sugar derivative that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in its ability to introduce stereochemical complexity and functional handles for constructing complex molecules, particularly in pharmaceutical research. This compound is essential for chemists and researchers in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for developing active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of nucleoside analogs, antiviral agents, and other complex therapeutic molecules.
• Glycochemistry Research: Used in the preparation of complex carbohydrates, glycoconjugates, and glycomimetics for biological studies and drug discovery.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic and stoichiometric asymmetric reactions to construct stereodefined centers.
• Agrochemical Development: Serves as a building block for creating novel, biologically active compounds with specific stereochemistry for crop protection.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals, flavors, fragrances, and advanced materials requiring precise molecular architecture.
• Academic & Process R&D: A valuable reagent for method development, route scouting, and scale-up studies in academic and industrial laboratories.

Basic Information

Product Name	2-O,3-O:5-O,6-o-Diisopropylidene-D-Mannose Oxime
CAS No.	35023-80-4
Molecular Formula	C12H19NO6
Molecular Weight	273.28 g/mol
Synonyms	1,2:5,6-Di-O-isopropylidene-α-D-mannofuranose oxime; Diacetone mannose oxime; D-Mannose, O,O'-(1-methylethylidene)oxime; 1,2:5,6-Di-O-isopropylidene-D-mannofuranose oxime; Isopropylidene-D-mannose oxime; D-Mannose oxime diisopropylidene derivative; 35023-80-4; Di-O-isopropylidene-D-mannose oxime
EINECS	Contact for details

Quality Control

Our 2-O,3-O:5-O,6-o-Diisopropylidene-D-Mannose Oxime is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and chiral purity analysis, to meet the stringent requirements of research and production applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.