Description

[1Ar,(-)]-1,1Aβ,2,3,3A,4,5,7Bβ-Octahydro-1,1,3Aα,7-Tetramethyl-6H-Cyclopropa[A]Naphthalene-6-One is a high-purity, specialized organic compound with a complex polycyclic structure. This compound serves as a valuable advanced intermediate or building block in sophisticated organic synthesis, particularly for the development of novel fragrance molecules, pharmaceuticals, and fine chemicals. It is primarily sought by R&D chemists and process development teams in the flavor & fragrance, pharmaceutical, and agrochemical industries for creating molecules with unique olfactory or biological properties.

Application

• Fragrance & Flavor Intermediate: A key building block for synthesizing novel musk compounds, amber notes, and other complex odorants for perfumery and flavor applications.
• Pharmaceutical Research: Used as a chiral synthon or core structure in the research and development of new active pharmaceutical ingredients (APIs), particularly in steroid-like or terpenoid-based drug discovery.
• Agrochemical Synthesis: Serves as an intermediate in the production of specialized pesticides or plant growth regulators that leverage its complex hydrocarbon framework.
• Fine Chemical Production: Employed in the synthesis of other high-value, low-volume specialty chemicals requiring its specific stereochemistry and functional groups.
• Academic & Industrial R&D: A valuable compound for methodological studies in organic chemistry, including catalysis, asymmetric synthesis, and natural product synthesis.

Basic Information

Item	Details
Product Name	[1Ar,(-)]-1,1Aβ,2,3,3A,4,5,7Bβ-Octahydro-1,1,3Aα,7-Tetramethyl-6H-Cyclopropa[A]Naphthalene-6-One
CAS No.	35008-18-5
Molecular Formula	C15H22O
Molecular Weight	218.33 g/mol
Synonyms	(-)-Ambroxide; (-)-Ambrox; (3aR,5aS,9aS,9bR)-3a,6,6,9a-Tetramethyldodecahydronaphtho[2,1-b]furan; (1R,2R,8aS)-1,2,5,5,8a-Pentamethyl-1,2,3,4,6,7,8,8a-octahydronaphthalen-1-ol; (-)-Ambroxan; (-)-Ambrox DL; Ambrox Super; Fixateur 404; Cetalox
EINECS	Contact for details

Quality Control

Our production of [1Ar,(-)]-1,1Aβ,2,3,3A,4,5,7Bβ-Octahydro-1,1,3Aα,7-Tetramethyl-6H-Cyclopropa[A]Naphthalene-6-One adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Products undergo rigorous analytical testing, including GC, HPLC, and chiral analysis, to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We can support compliance requirements for various applications, including those under IFRA guidelines for fragrance materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider filling the headspace with an inert gas such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 98.0%
Enantiomeric Purity (Chiral GC/HPLC)	≥ 99.0%
Melting Point	Contact for details
Specific Rotation [α]D20	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.