Description

Acetic Acid, [(Triphenylmethyl)Thio]- is a specialized organosulfur compound featuring a trityl-protected thioacetic acid moiety. This unique structure makes it a valuable reagent in synthetic organic chemistry, particularly for the controlled introduction of thioester or thiol functionalities under mild conditions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those containing sulfur heterocycles or thioether linkages.
• Peptide Chemistry & Bioconjugation: Used as a thioacetylation agent for modifying peptides, proteins, and other biomolecules, facilitating site-specific labeling or conjugation.
• Polymer Science & Material Modification: Acts as a functional monomer or cross-linking agent in the development of specialty polymers with tailored properties like adhesion or chemical resistance.
• Agrochemical Synthesis: Employed in the research and production of novel herbicides, fungicides, and insecticides that require specific sulfur-containing pharmacophores.
• Ligand & Catalyst Development: Useful for preparing sulfur-based ligands for transition metal catalysts used in asymmetric synthesis and coupling reactions.
• Organic Synthesis Reagent: Provides a protected form of thioacetic acid, allowing for selective deprotection and subsequent reactions in multi-step synthetic sequences.

Basic Information

Product Name	Acetic Acid, [(Triphenylmethyl)Thio]-
CAS No.	34914-36-8
Molecular Formula	C21H18O2S
Molecular Weight	334.43 g/mol
Synonyms	S-Trityl Thioacetate; Trityl Thioacetate; (Triphenylmethyl) Thioacetate; Acetic Acid Trityl Thioester; α-Acetylthiotriphenylmethane; Acetyl Trityl Sulfide; S-(Triphenylmethyl) Ethanethioate; Triphenylmethyl Thioacetate
EINECS	Contact for details

Quality Control

Our Acetic Acid, [(Triphenylmethyl)Thio]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon. Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.