Description

Cuprous Iodide Trimethylphosphite Complex is a specialized organocopper reagent widely used in organic synthesis for its unique reactivity profile. This complex is particularly valued for its ability to facilitate efficient carbon-carbon bond formation under mild conditions, offering chemists a powerful tool for constructing complex molecular architectures. It is an essential material for research and development laboratories in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel compounds.

Application

• Catalyst in Cross-Coupling Reactions: Employed as a catalyst or catalyst precursor in various palladium- or copper-catalyzed cross-coupling reactions, such as the Sonogashira coupling, for the synthesis of alkynes.
• Reagent in Conjugate Additions: Used as a source of a copper(I) nucleophile in 1,4-conjugate addition reactions to α,β-unsaturated carbonyl compounds.
• Synthesis of Heterocycles: A key reagent in the cyclization and annulation reactions used to construct nitrogen- and oxygen-containing heterocyclic compounds, which are common scaffolds in active pharmaceutical ingredients (APIs).
• Material Science Research: Utilized in the development of novel organometallic frameworks and precursors for copper-containing thin films or nanomaterials.
• Asymmetric Synthesis: Can be used in conjunction with chiral ligands to induce asymmetry in carbon-heteroatom bond-forming reactions.
• Pharmaceutical Intermediate Manufacturing: Plays a role in the multi-step synthesis of complex drug candidates and fine chemicals at the pilot and commercial scale.

Basic Information

Product Name	Cuprous Iodide Trimethylphosphite Complex
CAS No.	34836-53-8
Molecular Formula	C3H9CuIO3P
Molecular Weight	314.43 g/mol
Synonyms	Copper(I) Iodide Trimethyl Phosphite Complex; Trimethyl Phosphite-Copper(I) Iodide; (Trimethylphosphite)copper(I) Iodide; Cuprous Iodide-Trimethyl Phosphite (1:1); P(OCH3)3·CuI; TMP-CuI; CuI-P(OMe)3; Copper Iodide Trimethyl Phosphite Adduct
EINECS	Contact for details

Quality Control

Our Cuprous Iodide Trimethylphosphite Complex is manufactured under controlled conditions to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes rigorous analytical testing, including assay and identification, to confirm its identity and suitability for synthetic applications. A Certificate of Analysis (COA) detailing specific results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and transfer should be minimized under direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (CuI Complex)	≥ 95.0%
Solubility Test	Soluble in common organic solvents (e.g., DCM, THF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.