Description

Rel-(1R,2R,3S)-2,3-Dimethylcyclopropane-1-Carboxylic Acid is a high-purity, stereochemically defined cyclopropane derivative. This compound serves as a valuable chiral building block and intermediate in advanced organic synthesis, prized for its rigid, strained three-membered ring structure. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, where precise stereochemistry is critical for biological activity.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of antiviral, antibacterial, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the cyclopropane moiety can enhance metabolic stability and target specificity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to create enantiomerically pure compounds.
• Material Science Research: Investigated as a monomer or modifying agent for creating polymers with unique thermal and mechanical properties due to the strained ring system.
• Flavor and Fragrance Industry: Potential intermediate for synthesizing complex terpenoids and musk-like compounds with specific olfactory profiles.

Basic Information

Product Name	Rel-(1R,2R,3S)-2,3-Dimethylcyclopropane-1-Carboxylic Acid
CAS No.	34669-51-7
Molecular Formula	C7H12O2
Molecular Weight	128.17 g/mol
Synonyms	(1R,2R,3S)-2,3-Dimethylcyclopropanecarboxylic Acid; rel-(1R,2R,3S)-2,3-Dimethylcyclopropanecarboxylic Acid; 2,3-Dimethylcyclopropane-1-carboxylic Acid; NSC 169006; (1R,2R,3S)-2,3-Dimethyl-1-cyclopropanecarboxylic Acid; Cyclopropanecarboxylic acid, 2,3-dimethyl-, (1R,2R,3S)-rel-
EINECS	Contact for details

Quality Control

Our Rel-(1R,2R,3S)-2,3-Dimethylcyclopropane-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and cGMP manufacturing. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and stereochemical integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.