Description

1-Chloro-2,5-Dimethyl-4-Nitrobenzene (2-Chloro-5-Nitro-p-Xylene) is a versatile halogenated nitroaromatic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both electron-withdrawing and electron-donating substituents, makes it a valuable intermediate for creating complex molecules with specific functionalities. This compound is essential for manufacturers and R&D laboratories in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a substituted nitrobenzene scaffold.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and pesticides, where its chloronitro aromatic structure is incorporated into target molecules.
• Dye and Pigment Manufacturing: Serves as an intermediate for synthesizing azo dyes and other complex organic colorants.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for electron-transport materials or host materials in OLED fabrication.
• Liquid Crystal Intermediates: Utilized in the synthesis of advanced liquid crystal compounds for display technologies.
• Polymer Modification: Employed to introduce functional groups into polymer chains, altering physical or chemical properties.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for creating biaryl structures.
• Research & Development: Used in academic and industrial R&D for exploring new synthetic pathways and novel chemical entities.

Basic Information

Product Name	1-Chloro-2,5-Dimethyl-4-Nitrobenzene / 2-Chloro-5-Nitro-p-Xylene
CAS No.	34633-69-7
Molecular Formula	C8H8ClNO2
Molecular Weight	185.61 g/mol
Synonyms	2-Chloro-5-Nitro-p-Xylene; 1-Chloro-2,5-dimethyl-4-nitrobenzene; 4-Nitro-2,5-dimethylchlorobenzene; p-Xylene, 2-chloro-5-nitro-; 2,5-Dimethyl-4-nitrochlorobenzene; 2-Chloro-1,4-dimethyl-5-nitrobenzene; 5-Nitro-2-chloro-1,4-dimethylbenzene; Benzene, 1-chloro-2,5-dimethyl-4-nitro-
EINECS	Contact for details

Quality Control

Our 1-Chloro-2,5-Dimethyl-4-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) detailing identity, assay, and impurity profiles to support your quality assurance protocols. Our production adheres to cGMP principles where applicable, ensuring reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions. Keep the container tightly sealed when not in use to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	68°C - 72°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.