Description

(R)-(-)-n-(p-Tolylsulphonyl)Glutamic Acide CAS NO 34605-45-3 is a high-purity chiral sulfonamide derivative of glutamic acid, serving as a critical building block in asymmetric synthesis. Its value lies in its role as a versatile chiral auxiliary and resolving agent for the preparation of enantiomerically pure pharmaceutical intermediates. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require high stereochemical fidelity for advanced synthesis.

Application

• As a chiral auxiliary in asymmetric carbon-carbon bond-forming reactions.
• As a resolving agent for the separation of racemic mixtures of amines or acids.
• Key intermediate in the synthesis of pharmaceutical active ingredients (APIs) with specific stereochemistry.
• Building block for peptidomimetics and other bioactive molecules in medicinal chemistry research.
• Use in the development of agrochemicals such as herbicides and fungicides requiring chiral purity.
• Precursor for specialty catalysts and ligands used in homogeneous catalysis.
• Reference standard for analytical method development and quality control in chiral analysis.

Basic Information

Product Name	(R)-(-)-n-(p-Tolylsulphonyl)Glutamic Acide
CAS No.	34605-45-3
Molecular Formula	C12H15NO6S
Molecular Weight	301.32 g/mol
Synonyms	(R)-N-(4-Methylphenyl)sulfonylglutamic Acid; (R)-N-(p-Toluenesulfonyl)glutamic Acid; (R)-(-)-N-(p-Tolylsulfonyl)glutamic Acid; (2R)-2-[(4-Methylphenyl)sulfonylamino]pentanedioic Acid; (R)-Ts-Glu-OH; D-(-)-N-(p-Toluenesulfonyl)glutamic Acid; (R)-N-Tosylglutamic Acid; L-Glutamic Acid, N-[(4-methylphenyl)sulfonyl]-, (R)-
EINECS	Contact for details

Quality Control

Our (R)-(-)-n-(p-Tolylsulphonyl)Glutamic Acide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) documenting identity, purity, and chiral excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.