Description

(2Alpha,3Aalpha,4Alpha,7Alpha,7Abeta)-Octahydro-4,7-Methano-1H-Indene-2-Carboxylic Acid is a high-purity, specialized bicyclic carboxylic acid derivative with a complex, rigid molecular framework. This compound serves as a critical advanced pharmaceutical intermediate and a versatile chiral building block for synthesizing complex organic molecules. It is essential for research and production in the pharmaceutical, agrochemical, and fine chemical industries, where its unique stereochemistry enables the creation of high-value, biologically active compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug research.
• Agrochemical Synthesis: Used as a precursor in the manufacture of advanced pesticides and herbicides, leveraging its complex bicyclic structure for enhanced biological activity.
• Fine Chemical Production: Serves as a sophisticated building block for synthesizing specialty chemicals, flavors, fragrances, and performance materials.
• Asymmetric Catalysis & Ligand Synthesis: Its rigid, polycyclic structure makes it a valuable scaffold for developing novel chiral ligands and catalysts used in enantioselective synthesis.
• Academic & Industrial R&D: Employed in chemical research for studying reaction mechanisms, stereochemistry, and the synthesis of complex natural product analogs.
• Material Science Precursor: Potential use in creating novel polymers or additives with specific thermal or mechanical properties derived from its fused ring system.

Basic Information

Item	Details
Product Name	(2Alpha,3Aalpha,4Alpha,7Alpha,7Abeta)-Octahydro-4,7-Methano-1H-Indene-2-Carboxylic Acid
CAS No.	34562-01-1
Molecular Formula	C11H16O2
Molecular Weight	180.24 g/mol
Synonyms	Bicyclo[2.2.1]heptane-2-carboxylic acid, 1,3,3-trimethyl-; 1,3,3-Trimethylbicyclo[2.2.1]heptane-2-carboxylic acid; 2-Norbornanecarboxylic acid, 1,3,3-trimethyl-; Trimethyl-2-norbornanecarboxylic acid; Octahydro-4,7-methano-1H-indene-2-carboxylic acid; NSC 334365; (1R,2S,4R)-1,3,3-Trimethylbicyclo[2.2.1]heptane-2-carboxylic acid (stereoisomer)
EINECS	Contact for details

Quality Control

Our (2Alpha,3Aalpha,4Alpha,7Alpha,7Abeta)-Octahydro-4,7-Methano-1H-Indene-2-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and chiral analysis, to ensure identity, purity, and stereochemical integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures material suitability for demanding applications in GMP-grade pharmaceutical synthesis and advanced research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The container should be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.