Description

(2S,5E)-5-Ethylidenetetrahydro-2-(Hydroxymethyl)-3α-Methyl-6-Oxo-2H-Pyran-2β-Carboxylic Acid is a high-purity, stereochemically defined lactone derivative with significant synthetic utility. This compound serves as a versatile chiral building block and key intermediate in the synthesis of complex organic molecules, particularly in the pharmaceutical sector. It is essential for research and development chemists working on novel active pharmaceutical ingredients (APIs), fine chemicals, and advanced material science applications.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel therapeutic agents, including antibiotics and enzyme inhibitors.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex natural products and other high-value specialty chemicals.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development of new catalytic systems for stereoselective reactions.
• Academic & Industrial R&D: Serves as a standard or starting material in chemical research for method development and discovery chemistry.
• Process Chemistry: Utilized in scale-up studies and route optimization for the commercial production of advanced chemical entities.

Basic Information

Product Name	(2S,5E)-5-Ethylidenetetrahydro-2-(Hydroxymethyl)-3α-Methyl-6-Oxo-2H-Pyran-2β-Carboxylic Acid
CAS No.	34081-95-3
Molecular Formula	C10H14O5
Molecular Weight	214.22 g/mol
Synonyms	5-Ethylidenetetrahydro-2-(hydroxymethyl)-3α-methyl-6-oxo-2H-pyran-2β-carboxylic acid; (2S,5E)-5-Ethylidene-2-(hydroxymethyl)-3α-methyl-6-oxotetrahydro-2H-pyran-2β-carboxylic Acid; 2H-Pyran-2β-carboxylic acid, 5-ethylidenetetrahydro-2-(hydroxymethyl)-3α-methyl-6-oxo-, (2S,5E)-; Lactone derivative of 2-(hydroxymethyl)-3-methyl-6-oxo-5-ethylidene-tetrahydro-2H-pyran-2-carboxylic acid.
EINECS	Contact for details

Quality Control

Our (2S,5E)-5-Ethylidenetetrahydro-2-(Hydroxymethyl)-3α-Methyl-6-Oxo-2H-Pyran-2β-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.