Description

2’-(Acetylthio)Ethyl 2,3,4,6-Tetra-o-Acetyl--D-Glucopyranoside is a key protected thioglycoside intermediate in synthetic carbohydrate chemistry. This compound matters for its role as a versatile building block in the stereoselective synthesis of complex oligosaccharides and glycoconjugates. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel glycotherapeutics, vaccines, and diagnostic tools.

Application

• Glycoconjugate Synthesis: A critical precursor for the preparation of S-linked glycosides and thioglycoside donors used in oligosaccharide assembly.
• Pharmaceutical Intermediates: Serves as a building block in the research and development of carbohydrate-based drugs and prodrugs.
• Bioconjugation Chemistry: Used in the site-specific modification of proteins, peptides, and other biomolecules via its reactive thiol group after deprotection.
• Glycopolymer Research: Employed in the synthesis of novel polymeric materials with carbohydrate motifs for biomedical applications.
• Chemical Biology Probes: Facilitates the creation of labeled sugar analogs for studying glycosylation processes and carbohydrate-protein interactions.
• Standards and Reference Materials: Provides a high-purity standard for analytical method development and quality control in carbohydrate chemistry.

Basic Information

Product Name	2’-(Acetylthio)Ethyl 2,3,4,6-Tetra-o-Acetyl--D-Glucopyranoside
CAS No.	34044-34-3
Molecular Formula	C18H26O11S
Molecular Weight	450.46 g/mol
Synonyms	2'-(Acetylthio)ethyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside; 1-[(2-Acetylthio)ethyl] 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside; β-D-Glucopyranoside, 2'-(acetylthio)ethyl 2,3,4,6-tetra-O-acetyl-; S-Acetyl 2-thioethyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside; Protected thioglucose derivative; Acetylated thioglycosyl donor; 2-Thioethyl glycoside tetraacetate
EINECS	Contact for details

Quality Control

Our 2’-(Acetylthio)Ethyl 2,3,4,6-Tetra-o-Acetyl--D-Glucopyranoside is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity suitable for sensitive research applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.