Description

(R)-3,4-Dihydro-8-Hydroxy-6,7-Dimethoxy-3-Methyl-1H-2-Benzopyran-1-One is a high-purity chiral isochromanone derivative, a critical building block in advanced organic synthesis. Its defined stereochemistry and functional groups make it an invaluable intermediate for the development of novel pharmaceuticals and fine chemicals. This compound is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating enantiomerically pure active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of potential drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Asymmetric Synthesis: Serves as a versatile starting material or intermediate in catalytic asymmetric reactions to construct complex molecular architectures.
• Natural Product Synthesis: Used in the total or semi-synthesis of complex natural products containing the isochromanone or tetralone core structure.
• Agrochemical Research: Employed in the development of new, enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Chemical Reference Standard: Supplied as a high-purity analytical standard for method development, quality control, and regulatory submissions.
• Material Science Precursor: Investigated as a monomer or functional additive for the synthesis of specialized polymers and advanced materials.

Basic Information

Product Name	(R)-3,4-Dihydro-8-Hydroxy-6,7-Dimethoxy-3-Methyl-1H-2-Benzopyran-1-One
CAS No.	34019-32-4
Molecular Formula	C₁₂H₁₄O₅
Molecular Weight	238.24 g/mol
Synonyms	(R)-8-Hydroxy-6,7-dimethoxy-3-methyl-3,4-dihydro-1H-isochromen-1-one; (R)-8-Hydroxy-6,7-dimethoxy-3-methyl-1-oxo-1,3,4,5-tetrahydro-2-benzopyran; (R)-3-Methyl-8-hydroxy-6,7-dimethoxyisochroman-1-one; (R)-3,4-Dihydro-8-hydroxy-6,7-dimethoxy-3-methyl-1H-2-benzopyran-1-one; (R)-Homopterocarpin derivative; (R)-Enantiomer of 34019-32-4; (R)-Isochroman-1-one derivative
EINECS	Contact for details

Quality Control

Our (R)-3,4-Dihydro-8-Hydroxy-6,7-Dimethoxy-3-Methyl-1H-2-Benzopyran-1-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure high enantiomeric excess (e.e.) and chemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent potential oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.