Description

(1Alpha,2Beta,5Alpha)-5-(1,1-Dimethylethyl)-2-Hydroxycyclohexanecarboxylic Acid is a high-purity, sterically hindered chiral cyclohexane derivative. This compound matters as a sophisticated building block and intermediate for the synthesis of complex molecules, offering precise stereochemistry critical for advanced applications. It is needed by research and development teams in the pharmaceutical and fine chemical industries, particularly for creating novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in steroid-like or complex alicyclic compound synthesis.
• Asymmetric Catalyst Ligand Precursor: Used in the preparation of chiral ligands for metal-catalyzed asymmetric reactions, enhancing enantioselectivity.
• Fine Chemical Synthesis: Serves as a versatile building block for creating specialty chemicals, flavors, and fragrances requiring specific stereochemical configurations.
• Material Science Research: Employed in the development of advanced polymers and liquid crystals where the rigid, substituted cyclohexane core imparts desired physical properties.
• Agrochemical Intermediate: Potential use in the synthesis of novel, high-efficacy crop protection agents with complex molecular architectures.

Basic Information

Product Name	(1Alpha,2Beta,5Alpha)-5-(1,1-Dimethylethyl)-2-Hydroxycyclohexanecarboxylic Acid
CAS No.	33964-82-8
Molecular Formula	C12H22O3
Molecular Weight	214.30 g/mol
Synonyms	5-tert-Butyl-2-hydroxycyclohexanecarboxylic acid (1α,2β,5α)-; (1α,2β,5α)-5-tert-Butyl-2-hydroxycyclohexanecarboxylic acid; 5-(tert-Butyl)-2-hydroxycyclohexanecarboxylic acid (1α,2β,5α)-; 5-tert-Butyl-2-hydroxy-1,2,3,4,5,6-hexahydrobenzoic acid (stereoisomer); Chiral tert-butyl cyclohexane carboxylic acid derivative; Sterically hindered hydroxy acid intermediate
EINECS	Contact for details

Quality Control

Our (1Alpha,2Beta,5Alpha)-5-(1,1-Dimethylethyl)-2-Hydroxycyclohexanecarboxylic Acid is produced under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high chemical purity and stereochemical integrity. Certificates of Analysis (COA) detailing identity, purity (HPLC/Chiral HPLC), and impurity profiles are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.