Description

3-Buten-2-One, 4-(Methylthio)-, (Z)- (8Ci,9Ci) is a specialized sulfur-containing α,β-unsaturated ketone, a key structural motif in organic synthesis. This compound matters as a versatile building block for introducing the (Z)-configured methylthio enone functionality into target molecules, enabling the synthesis of complex heterocycles and bioactive intermediates. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those containing sulfur heterocycles or specific chiral centers.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the methylthio group can act as a leaving group or a key pharmacophore.
• Fine Chemical Building Block: Employed in multi-step organic synthesis for constructing complex natural products, flavors, and fragrances.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of advanced polymers with specific optical or electronic properties.
• Chemical Biology Probe: Utilized in the design and synthesis of activity-based probes for studying enzyme mechanisms and protein interactions.

Basic Information

Product Name	3-Buten-2-One, 4-(Methylthio)-, (Z)- (8Ci,9Ci)
CAS No.	33944-93-3
Molecular Formula	C5H8OS
Molecular Weight	116.18 g/mol
Synonyms	(Z)-4-(Methylthio)-3-buten-2-one; (Z)-4-Methylsulfanylbut-3-en-2-one; (Z)-1-(Methylthio)-1-buten-3-one; (Z)-4-(Methylmercapto)-3-buten-2-one; cis-4-(Methylthio)-3-buten-2-one; 3-Buten-2-one, 4-(methylthio)-, (Z)-; 4-(Methylthio)-3-buten-2-one (Z)-isomer
EINECS	Contact for details

Quality Control

Our 3-Buten-2-One, 4-(Methylthio)-, (Z)- is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatographic purity analysis and structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in the original packaging or amber glass until use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0% (Area %)
Isomeric Purity (Z-isomer)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.