Description

2-Bromo-1-(Bromomethyl)-4-Chlorobenzene is a versatile halogenated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both bromomethyl and bromo substituents on a chlorobenzene ring, makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key starting material or intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring complex halogenated aromatic cores.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides where the benzyl bromide moiety allows for further functionalization.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized phosphine ligands or metal-organic catalysts used in cross-coupling reactions.
• Material Science Research: Employed in the creation of novel monomers for polymers or advanced organic materials with specific electronic properties.
• Chemical Biology Probes: Useful for synthesizing molecular probes where the reactive bromomethyl group can be used for bioconjugation or labeling.
• Custom Synthesis and R&D: A critical reagent for contract research organizations (CROs) and academic laboratories exploring new synthetic methodologies and compound libraries.

Basic Information

Product Name	2-Bromo-1-(Bromomethyl)-4-Chlorobenzene
CAS No.	33924-45-7
Molecular Formula	C7H5Br2Cl
Molecular Weight	284.38 g/mol
Synonyms	1,2-Dibromo-4-Chlorotoluene; 4-Chloro-1,2-bis(bromomethyl)benzene; 2-Bromo-α-(bromomethyl)-4-chlorotoluene; 4-Chloro-α,2-dibromotoluene; 1-(Bromomethyl)-2-bromo-4-chlorobenzene; Benzene, 2-bromo-1-(bromomethyl)-4-chloro-; α,2-Dibromo-4-chlorotoluene
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-(Bromomethyl)-4-Chlorobenzene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of GMP and ISO standards for fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and reducing agents. Recommended storage temperature is between 2°C and 8°C for long-term stability. Keep container tightly sealed when not in use to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	68°C - 72°C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.