Description

trans-Dimethyl-2,5-Dihydrofuran-3(2H)-One is a high-purity, specialized heterocyclic building block with significant synthetic utility. This compound is valued for its role as a versatile intermediate in the synthesis of complex organic molecules, particularly in fine chemical and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists working in pharmaceutical, agrochemical, and advanced material sectors.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of novel therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides due to its reactive furanone structure.
• Flavor & Fragrance Chemistry: Serves as a precursor for creating specific lactone and furanone-based flavor compounds, contributing to complex sensory profiles.
• Material Science Research: Employed as a monomer or building block in the development of novel polymers and functional materials with specific optical or electronic properties.
• Organic Synthesis & Methodology: A valuable substrate in academic and industrial research for developing new catalytic reactions, such as asymmetric hydrogenations or cycloadditions.
• Fine Chemical Production: Utilized in the multi-step synthesis of specialty chemicals where its defined stereochemistry is critical for the final product's performance.

Basic Information

Product Name	trans-Dimethyl-2,5-Dihydrofuran-3(2H)-One
CAS No.	33909-95-4
Molecular Formula	C6H8O2
Molecular Weight	112.13 g/mol
Synonyms	trans-2,5-Dimethyl-2,5-dihydrofuran-3(2H)-one; (2R,5R)-2,5-Dimethyl-2,5-dihydrofuran-3(2H)-one; (2S,5S)-2,5-Dimethyl-2,5-dihydrofuran-3(2H)-one; 3(2H)-Furanone, 2,5-dihydro-2,5-dimethyl-, trans-; 2,5-Dimethyl-2,5-dihydro-3-furanone; Dihydro-2,5-dimethyl-3(2H)-furanone; trans-2,5-Dimethyl-3(2H)-furanone
EINECS	Contact for details

Quality Control

Our trans-Dimethyl-2,5-Dihydrofuran-3(2H)-One is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including GC, HPLC, and NMR to verify identity, purity, and isomeric composition. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. Our quality systems support development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Isomeric Purity (trans-)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.