Description

4-Aminoisophthalic Acid is a high-purity aromatic dicarboxylic acid derivative featuring an amine functional group, making it a versatile and valuable building block in advanced organic synthesis. This compound is essential for creating complex molecular architectures where precise control over both acidity and reactivity is required. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty polymer sectors for developing active ingredients, ligands, and high-performance materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring isophthalic acid backbones with modifiable amine sites.
• Agrochemical Synthesis: Used in the development of modern herbicides, fungicides, and plant growth regulators that benefit from its bifunctional reactivity.
• Metal-Organic Frameworks (MOFs): Serves as an organic linker or ligand in the construction of porous coordination polymers and MOFs for gas storage, separation, and catalysis.
• Polymer & Resin Modifier: Incorporated into polyamides, polyimides, and epoxy resins to enhance thermal stability, mechanical strength, and adhesion properties.
• Dye & Pigment Manufacturing: Intermediate for producing azo dyes and high-performance pigments where the amino and carboxylic acid groups allow for color tuning and improved fastness.
• Cross-coupling Reactions: Valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) for creating complex biaryl structures.

Basic Information

Product Name	4-Aminoisophthalic Acid
CAS No.	33890-03-8
Molecular Formula	C8H7NO4
Molecular Weight	181.15 g/mol
Synonyms	5-Aminobenzene-1,3-dicarboxylic Acid; 5-Aminoisophthalic Acid; 4-Amino-1,3-benzenedicarboxylic Acid; 1,3-Benzenedicarboxylic acid, 5-amino-; AIA; 4-AIPA
EINECS	Contact for details

Quality Control

Our 4-Aminoisophthalic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.