Description

5,7-Dihydroxy-3,8-Dimethoxyflavone is a specialized polymethoxyflavone derivative, a subclass of flavonoids known for their significant biological activity. This compound matters for its role as a high-purity reference standard and a key intermediate in advanced research and development. It is primarily needed by the pharmaceutical, nutraceutical, and life science industries for applications in drug discovery, analytical method development, and the study of bioactive natural products.

Application

• Pharmaceutical Reference Standard: Used for the identification, purity assessment, and quantification of active flavonoid components in drug formulations and herbal extracts via HPLC or LC-MS.
• Biochemical Research: Serves as a critical tool in studying structure-activity relationships (SAR), enzyme inhibition, and cellular signaling pathways related to flavonoid bioactivity.
• Nutraceutical & Cosmetic Ingredient Development: Investigated for its potential antioxidant and skin-beneficial properties in the formulation of advanced dietary supplements and cosmeceuticals.
• Academic & Industrial R&D: Employed as a building block or model compound in synthetic chemistry and medicinal chemistry programs targeting novel therapeutic agents.
• Quality Control Laboratories: Essential for calibrating analytical instruments and validating testing methods to ensure the quality and consistency of flavonoid-containing products.

Basic Information

Product Name	5,7-Dihydroxy-3,8-Dimethoxyflavone
CAS No.	33803-42-8
Molecular Formula	C₁₇H₁₄O₇
Molecular Weight	330.29 g/mol
Synonyms	3',5-Dihydroxy-4',7-dimethoxyflavone; 5,7-Dihydroxy-3,8-dimethoxy-2-phenyl-4H-chromen-4-one; 3,8-Dimethoxy-5,7-dihydroxyflavone; 5,7-Dihydroxy-3,8-dimethoxyflavone; NSC 407340; Flavone, 5,7-dihydroxy-3,8-dimethoxy-
EINECS	Contact for details

Quality Control

Our 5,7-Dihydroxy-3,8-Dimethoxyflavone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) detailing all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive nature, prolonged exposure to light should be avoided. For long-term storage, consider under an inert atmosphere to minimize potential oxidation.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.