Description

(Cis)-Dihydro-2,5-Dimethylfuran-3(2H)-One is a versatile chiral lactone building block of significant interest in fine chemical synthesis. Its defined stereochemistry and functionalized furanone core make it a valuable precursor for creating complex molecules with specific spatial orientations. This compound is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring specific stereocenters.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where its structure imparts specific biological activity.
• Flavor and Fragrance Ingredient: Serves as a precursor for creating lactone-based flavor compounds, contributing to creamy, buttery, or fruity notes in advanced flavor formulations.
• Organic Synthesis Building Block: Employed in asymmetric synthesis and medicinal chemistry research for constructing complex heterocyclic compounds and natural product analogs.
• Ligand and Catalyst Development: Its structure can be utilized to develop novel chiral ligands and organocatalysts for stereoselective transformations.
• Material Science Research: Investigated as a monomer or modifying agent for specialty polymers with unique degradation or optical properties.

Basic Information

Product Name	(Cis)-Dihydro-2,5-Dimethylfuran-3(2H)-One
CAS No.	33794-61-5
Molecular Formula	C6H10O2
Molecular Weight	114.14 g/mol
Synonyms	(3R,5S)-3,5-Dimethyldihydrofuran-2(3H)-one; (3S,5R)-3,5-Dimethyldihydrofuran-2(3H)-one; cis-3,5-Dimethyltetrahydrofuran-2-one; (cis)-3,5-Dimethyl-dihydro-furan-2-one; 2(3H)-Furanone, dihydro-3,5-dimethyl-, cis-; 3,5-Dimethyltetrahydro-2-furanone (cis); Lactone of 3,5-Dimethyl-4-hydroxyvaleric acid
EINECS	Contact for details

Quality Control

Our (Cis)-Dihydro-2,5-Dimethylfuran-3(2H)-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by GC or HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.