Description

2H-Pyran-4-Ol, Tetrahydro-2-Methyl-, (2S-Cis)- is a chiral, saturated heterocyclic alcohol of significant synthetic utility. This compound serves as a valuable building block and chiral intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and fine chemical sectors. It is primarily sought after by research and development chemists and process engineers for its role in constructing stereochemically defined molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), especially in antiviral, anti-inflammatory, and central nervous system (CNS) drug candidates.
• Asymmetric Synthesis: Used as a chiral auxiliary or starting material in stereoselective reactions to introduce the tetrahydro-2-methylpyran-4-ol moiety.
• Flavor & Fragrance Industry: Potential precursor for the synthesis of specific, high-value aroma chemicals and flavorants due to its oxygenated heterocyclic structure.
• Agrochemical Research: Intermediate in the synthesis of novel herbicides, fungicides, or plant growth regulators requiring specific stereochemistry.
• Material Science: Monomer or co-monomer for specialized polymers where the chiral center and hydroxyl group can influence polymer properties.
• Academic & Contract Research: Employed in methodological studies and custom synthesis projects within university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	2H-Pyran-4-Ol, Tetrahydro-2-Methyl-, (2S-Cis)-
CAS No.	33747-08-9
Molecular Formula	C6H12O2
Molecular Weight	116.16 g/mol
Synonyms	(2S,4S)-2-Methyltetrahydro-2H-pyran-4-ol; (2S-cis)-2-Methyltetrahydro-4H-pyran-4-ol; (-)-cis-2-Methyl-4-hydroxytetrahydropyran; cis-2-Methyltetrahydropyran-4-ol; 4-Hydroxy-2-methyltetrahydropyran; Tetrahydro-2-methyl-2H-pyran-4-ol; 2-Methyl-4-hydroxytetrahydropyran
EINECS	Contact for details

Quality Control

Every batch of 2H-Pyran-4-Ol, Tetrahydro-2-Methyl-, (2S-Cis)- is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and enantiomeric excess meet your project requirements. A detailed Certificate of Analysis (COA) with chromatographic and spectroscopic data is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.