Description

1-tert-Butyl-3-Methoxybenzene is a substituted aromatic compound featuring both a tert-butyl and a methoxy functional group on the benzene ring. This unique structure makes it a valuable intermediate and building block in advanced organic synthesis, particularly for creating complex molecules with specific steric and electronic properties. It is primarily sought after by pharmaceutical, agrochemical, and specialty chemical manufacturers for research and production processes.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring bulky, lipophilic substituents.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and pesticides where the tert-butyl-methoxybenzene scaffold contributes to biological activity and stability.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing specialized ligands used in catalytic systems for asymmetric synthesis and polymerization.
• Fragrance and Flavor Chemistry: Employed as an intermediate for creating specific aromatic compounds used in high-value fragrance and flavor formulations.
• Material Science Research: Utilized in the development of organic semiconductors, liquid crystals, and polymers where its molecular structure can tune material properties.
• Organic Synthesis Building Block: Provides a versatile platform for further functionalization, including electrophilic aromatic substitution and coupling reactions, in custom synthesis projects.

Basic Information

Product Name	1-tert-Butyl-3-Methoxybenzene
CAS No.	33733-83-4
Molecular Formula	C11H16O
Molecular Weight	164.24 g/mol
Synonyms	3-tert-Butylanisole; 3-Methoxy-1-tert-butylbenzene; 1-tert-Butyl-3-methoxybenzene; m-tert-Butylanisole; 3-(tert-Butyl)anisole; Anisole, 3-(1,1-dimethylethyl)-; Benzene, 1-(1,1-dimethylethyl)-3-methoxy-
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl-3-Methoxybenzene is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistent composition. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality system is designed to meet the stringent requirements of GMP and ISO standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and heat sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.