Description

1,2-Cyclobutanedione CAS NO 33689-28-0 is a highly reactive diketone compound characterized by its strained four-membered ring structure. This unique molecular architecture makes it a valuable and versatile building block in advanced organic synthesis and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular frameworks.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing complex, strained ring systems.
• Organic Synthesis Building Block: Used in cycloaddition reactions, ring-expansion protocols, and as a precursor for heterocyclic compounds like furans and pyrroles.
• Agrochemical Research: Serves as a starting material for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Investigated as a monomer or cross-linking agent for producing polymers with specific thermal or mechanical properties.
• Flavor & Fragrance Chemistry: Acts as a potential intermediate for synthesizing specific flavoring agents and aroma chemicals.
• Academic & Institutional Research: Employed in mechanistic studies and the development of new synthetic methodologies due to its high reactivity.

Basic Information

Product Name	1,2-Cyclobutanedione
CAS No.	33689-28-0
Molecular Formula	C4H4O2
Molecular Weight	84.07 g/mol
Synonyms	Cyclobutane-1,2-dione; 1,2-Diketocyclobutane; Cyclobutanedione; 1,2-Dioxocyclobutane; [4]Annulene-1,2-dione
EINECS	Contact for details

Quality Control

Our 1,2-Cyclobutanedione is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity and purity. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	Yellow to brown crystalline solid or liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.