Description

(2R)-2β-Hydroxy-6β-(Hydroxymethyl)-5,6-Dihydro-2H-Pyran-5-One CAS NO 33647-74-4 is a high-purity chiral lactone derivative, a key synthetic intermediate and building block in advanced organic synthesis. Its defined stereochemistry and functional groups make it a valuable precursor for constructing complex molecular architectures with precise spatial orientation. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of complex drug candidates, particularly in antiviral, anticancer, and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where specific stereochemistry is required for biological activity.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and other high-value specialty chemicals requiring defined lactone structures.
• Academic & Industrial Research: A valuable reagent for methodological studies in asymmetric synthesis, catalysis, and natural product total synthesis.
• Material Science: Potential monomer or modifier for creating specialized polymers with unique degradation or functional properties.

Basic Information

Product Name	(2R)-2β-Hydroxy-6β-(Hydroxymethyl)-5,6-Dihydro-2H-Pyran-5-One
CAS No.	33647-74-4
Molecular Formula	C7H10O4
Molecular Weight	158.15 g/mol
Synonyms	(2R,6R)-6-(Hydroxymethyl)-5,6-dihydro-2H-pyran-2,5(3H)-dione; (2R,6R)-6-(Hydroxymethyl)-5,6-dihydro-2H-pyran-2,5-diol-5-one; 2R,6R-Dihydroxy-6-hydroxymethyl-5,6-dihydro-2H-pyran-5-one; (2R,6R)-Dihydroxy-6-hydroxymethyl-5,6-dihydro-2H-pyran-5-one; (2R,6R)-6-(Hydroxymethyl)-2,5-dihydroxy-5,6-dihydro-2H-pyran-5-one; (2R)-2-Hydroxy-6-(hydroxymethyl)-5,6-dihydro-2H-pyran-5-one; Chiral Dihydroxypyranone
EINECS	Contact for details

Quality Control

Our (2R)-2β-Hydroxy-6β-(Hydroxymethyl)-5,6-Dihydro-2H-Pyran-5-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and stereochemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.