Description

(2S,4Aα)-Decahydro-8α,8Aα-Dimethyl-α-Methylene-4-Oxo-2α-Naphthaleneacetic Acid is a high-purity, complex organic intermediate with a defined stereochemistry, making it a critical building block for advanced synthesis. Its value lies in its precise molecular architecture, which is essential for producing compounds with specific biological or material properties. This product is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new therapeutic agents, particularly in steroid-like or complex terpenoid-based drug candidates.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and plant growth regulators that require specific stereochemical configurations for optimal activity.
• Organic Synthesis Research: Acts as a versatile starting material or intermediate in academic and industrial laboratories for constructing complex polycyclic frameworks.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals, including fragrances, flavors, and advanced material precursors.
• Process Development & Scale-up: Supports process chemistry teams in optimizing synthetic routes from laboratory to pilot and commercial scale.

Basic Information

Product Name	(2S,4Aα)-Decahydro-8α,8Aα-Dimethyl-α-Methylene-4-Oxo-2α-Naphthaleneacetic Acid
CAS No.	33596-80-4
Molecular Formula	C₁₅H₂₂O₃
Molecular Weight	250.33 g/mol
Synonyms	2-Naphthaleneacetic acid, decahydro-8,8a-dimethyl-α-methylene-4-oxo-, (2S,4aα,8aα)-; (2S,4aα,8aα)-Decahydro-8,8a-dimethyl-α-methylene-4-oxo-2-naphthaleneacetic acid; 8,8a-Dimethyl-α-methylenedecahydro-4-oxo-2-naphthaleneacetic acid; Podocarpic acid derivative; A key intermediate for forskolin synthesis
EINECS	Contact for details

Quality Control

Our (2S,4Aα)-Decahydro-8α,8Aα-Dimethyl-α-Methylene-4-Oxo-2α-Naphthaleneacetic Acid is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including chiral purity verification, to meet the exacting standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.