Description

17β,19-Bis(Acetyloxy)-3β-Fluoro-5-Hydroxy-5β-Androstan-6-One is a high-purity, fluorinated steroid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate for the creation of novel steroidal drugs, particularly those targeting hormonal pathways and metabolic disorders. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of next-generation therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of potent fluorinated corticosteroid analogs and other bioactive steroid molecules.
• Research Chemical: Used in academic and industrial research to study structure-activity relationships (SAR) of modified steroids and their receptor interactions.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in steroid manufacturing.
• Process Development: Employed in scaling up synthetic routes for new chemical entities (NCEs) under Good Manufacturing Practice (GMP) conditions.
• Metabolite Synthesis: Used to synthesize potential metabolites for pharmacological and toxicological profiling of parent steroid drugs.

Basic Information

Product Name	17β,19-Bis(Acetyloxy)-3β-Fluoro-5-Hydroxy-5β-Androstan-6-One
CAS No.	33547-32-9
Molecular Formula	C23H31FO6
Molecular Weight	422.49 g/mol
Synonyms	3β-Fluoro-5β-hydroxy-17β,19-bis(acetyloxy)-5β-androstan-6-one; 3β-Fluoro-5β-hydroxy-17β,19-diacetoxy-5β-androstan-6-one; 17β,19-Diacetoxy-3β-fluoro-5β-hydroxy-5β-androstan-6-one; 5β-Androstan-6-one, 17β,19-bis(acetyloxy)-3β-fluoro-5-hydroxy-; Fluorinated Androstane Derivative; 33547-32-9 (CAS)
EINECS	Contact for details

Quality Control

Our 17β,19-Bis(Acetyloxy)-3β-Fluoro-5-Hydroxy-5β-Androstan-6-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a detailed Certificate of Analysis (COA). We adhere to relevant industry standards to support our clients' research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.