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17β,19-Bis(Acetyloxy)-3β-Fluoro-5-Hydroxy-5α-Androstan-6-One CAS NO 33547-31-8


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CAS No.:33547-31-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

17β,19-Bis(Acetyloxy)-3β-Fluoro-5-Hydroxy-5α-Androstan-6-One is a high-purity, fluorinated steroid derivative with a complex and specific molecular structure. This compound is a critical advanced intermediate for the synthesis of novel steroidal pharmaceuticals, offering researchers precise control over molecular architecture. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing next-generation therapeutic agents, particularly in the fields of endocrinology and oncology.

Application

  • Pharmaceutical Intermediate: A key building block in the multi-step synthesis of potent steroidal drug candidates, including potential anti-inflammatory and anti-cancer agents.
  • Research Chemical: Used in academic and industrial research to study structure-activity relationships (SAR) of fluorinated steroids and their biological effects.
  • Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
  • Biochemical Probe: Employed in metabolic studies to investigate steroid hormone pathways and enzyme interactions due to its modified structure.
  • Process Development: Used for scaling up and optimizing synthetic routes for complex steroid molecules in pilot plant and manufacturing settings.

Basic Information

Product Name 17β,19-Bis(Acetyloxy)-3β-Fluoro-5-Hydroxy-5α-Androstan-6-One
CAS No. 33547-31-8
Molecular Formula C23H31FO6
Molecular Weight 422.49 g/mol
Synonyms 3β-Fluoro-5-hydroxy-5α-androstane-6,17-dione 17,19-diacetate; 3β-Fluoro-5α-androstane-5,6,17-trione 17,19-diacetate; 17β,19-Diacetoxy-3β-fluoro-5-hydroxy-5α-androstan-6-one; 3β-Fluoro-5-hydroxy-6-oxo-5α-androstan-17β-yl acetate 19-acetate; 5α-Androstan-6-one, 17,19-bis(acetyloxy)-3-fluoro-5-hydroxy-, (3β,5α,17β)-; Fluoxymesterone related compound F (common pharmaceutical impurity name).
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Quality Control

Our 17β,19-Bis(Acetyloxy)-3β-Fluoro-5-Hydroxy-5α-Androstan-6-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) with batch-specific data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Single Unknown Impurity (HPLC) ≤ 0.5%
Total Impurities (HPLC) ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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