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Benzyl 2-Acetamido-2-Deoxy-6-o-Triphenyl-Methyl-α-D-Glucopyranoside CAS NO 33493-71-9


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CAS No.:33493-71-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Benzyl 2-Acetamido-2-Deoxy-6-o-Triphenyl-Methyl-α-D-Glucopyranoside is a key protected monosaccharide derivative, specifically a glucosamine building block with orthogonal protecting groups. This compound is essential for the controlled, stepwise synthesis of complex oligosaccharides and glycoconjugates in carbohydrate chemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel glycotherapeutics, vaccines, and diagnostic tools.

Application

  • Glycochemistry Research: A fundamental building block for the solid-phase and solution-phase synthesis of complex oligosaccharides and glycans.
  • Pharmaceutical Intermediates: Serves as a critical precursor in the synthesis of glycosylated drug candidates, including antibiotics and anticancer agents.
  • Glycoconjugate Vaccine Development: Used to construct well-defined carbohydrate antigens for conjugation to carrier proteins.
  • Enzyme Substrate & Inhibitor Synthesis: Employed in the preparation of substrates or inhibitors for glycosidases and glycosyltransferases.
  • Glycochip & Diagnostic Reagent Fabrication: Acts as a starting material for creating carbohydrate arrays and labeled probes for binding studies.
  • Neoglycoprotein Production: Facilitates the chemical attachment of specific carbohydrate motifs to proteins for structural and functional studies.

Basic Information

Product Name Benzyl 2-Acetamido-2-Deoxy-6-o-Triphenyl-Methyl-α-D-Glucopyranoside
CAS No. 33493-71-9
Molecular Formula C35H37NO6
Molecular Weight 567.68 g/mol
Synonyms Benzyl 2-acetamido-2-deoxy-6-O-trityl-α-D-glucopyranoside; Benzyl 2-Acetamido-2-Deoxy-6-O-Triphenylmethyl-α-D-Glucopyranoside; Benzyl 2-Acetamido-6-O-trityl-2-deoxy-α-D-glucopyranoside; α-D-Glucopyranoside, benzyl 2-(acetylamino)-2-deoxy-6-O-triphenylmethyl-; GlcNAc(α1)-OBn 6-O-Trt derivative; N-Acetyl-6-O-trityl-D-glucosaminyl α-benzyl glycoside; Protected N-Acetylglucosamine benzyl glycoside
EINECS Contact for details

Quality Control

Our Benzyl 2-Acetamido-2-Deoxy-6-o-Triphenyl-Methyl-α-D-Glucopyranoside is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and optical rotation measurement, to ensure it meets the high standards required for synthetic chemistry. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Specific Rotation [α]²⁰D Contact for details
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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