Description

2-[(Trimethylsilyl)Oxy]Benzophenone is a specialized organosilicon-protected derivative of benzophenone, serving as a crucial synthetic intermediate and protecting group reagent. Its primary value lies in its ability to mask reactive hydroxyl groups under harsh reaction conditions, enabling complex multi-step synthesis in sensitive chemical environments. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, reliable building blocks for developing active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly where hydroxyl protection is required during peptide coupling or other sensitive reactions.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its protective group chemistry allows for the creation of specific active isomers.
• Polymer & Material Science: Acts as a monomer or modifying agent in the development of specialty polymers, including photosensitive resins and advanced coatings.
• Organic Synthesis Reagent: Employed as a versatile protecting group for phenols and alcohols in multi-step laboratory and industrial-scale organic synthesis.
• UV Initiator Precursor: Serves as a synthetic precursor for specialized photoinitiators used in UV-curable inks, adhesives, and coatings.
• Chemical Research & Development: A valuable tool for medicinal chemistry and process chemistry R&D for exploring new synthetic pathways.

Basic Information

Product Name	2-[(Trimethylsilyl)Oxy]Benzophenone
CAS No.	33342-95-9
Molecular Formula	C16H18O2Si
Molecular Weight	270.40 g/mol
Synonyms	2-(Trimethylsiloxy)benzophenone; o-(Trimethylsiloxy)benzophenone; Benzophenone, 2-[(trimethylsilyl)oxy]-; 2-Hydroxybenzophenone trimethylsilyl ether; 2-Benzoylphenyl trimethylsilyl ether; TMS-protected 2-hydroxybenzophenone; (2-Benzoylphenoxy)trimethylsilane
EINECS	Contact for details

Quality Control

Our 2-[(Trimethylsilyl)Oxy]Benzophenone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and Karl Fischer titration for moisture content. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your internal quality standards and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.