Description

n-(Trimethylsilyl)-5-[(Trimethylsilyl)oxy]-1-naphthalenamine is a specialized organosilicon compound featuring dual trimethylsilyl (TMS) protecting groups on the amine and phenolic hydroxyl functionalities of a naphthalene core. This compound matters as a crucial synthetic intermediate and protecting group reagent, enabling advanced organic synthesis in sensitive environments where standard functional groups are incompatible. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Used in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly where protection of amine and phenol groups is required.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and plant growth regulators.
• Advanced Material Precursor: Employed in the research and development of organic semiconductors, liquid crystals, and photoresist materials.
• Protecting Group Reagent: Utilized in complex organic synthesis to temporarily mask reactive amine and hydroxyl sites, allowing selective reactions at other positions.
• Chemical Research & Development: A valuable tool for academic and industrial research in methodology development and total synthesis of natural products.
• Dye and Pigment Intermediate: Acts as a precursor in the synthesis of specialized naphthalene-based dyes and colorants.

Basic Information

Product Name	n-(Trimethylsilyl)-5-[(Trimethylsilyl)oxy]-1-naphthalenamine
CAS No.	33285-82-4
Molecular Formula	C16H25NOSi2
Molecular Weight	303.55 g/mol
Synonyms	1-Naphthalenamine, N-(trimethylsilyl)-5-[(trimethylsilyl)oxy]-; 5-[(Trimethylsilyl)oxy]-N-(trimethylsilyl)-1-naphthalenamine; 1-Naphthylamine, N,5-bis(trimethylsilyl)-; Bis(trimethylsilyl)-1,5-naphthalenediamine derivative; 1,5-Bis(trimethylsilyloxy)naphthalene amine; TMS-protected 5-amino-1-naphthol; N,O-Bis(trimethylsilyl)-5-amino-1-naphthol
EINECS	Contact for details

Quality Control

Our n-(Trimethylsilyl)-5-[(Trimethylsilyl)oxy]-1-naphthalenamine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our commitment to quality supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.