Description

(17Beta)-3,3-[Ethylenebis(Oxy)]-17-Hydroxyandrost-5-Ene-17-Carbonitrile is a high-purity steroidal nitrile derivative, serving as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis. Its value lies in its unique molecular structure, which is engineered for specific chemical transformations and biological activity modulation. This compound is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical producers focused on steroid chemistry, drug discovery, and the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel steroidal drugs and active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new therapeutic agents targeting hormone receptors.
• Fine Chemical Synthesis: Acts as a specialized building block for constructing complex molecular architectures in custom synthesis and process development.
• Biochemical Research: Employed as a tool compound in biochemical assays to study enzyme inhibition and metabolic pathways involving steroid hormones.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	(17Beta)-3,3-[Ethylenebis(Oxy)]-17-Hydroxyandrost-5-Ene-17-Carbonitrile
CAS No.	33261-95-9
Molecular Formula	C22H29NO3
Molecular Weight	355.47 g/mol
Synonyms	17β-Hydroxy-3,3-ethylenedioxyandrost-5-en-17-carbonitrile; 3,3-Ethylenedioxy-17β-hydroxyandrost-5-en-17-carbonitrile; (17β)-3,3-(Ethylenedioxy)-17-hydroxyandrost-5-en-17-carbonitrile; 17-Cyano-3,3-ethylenedioxyandrost-5-en-17β-ol; Steroid Nitrile Intermediate; Androstene Carbonitrile Derivative; 33261-95-9
EINECS	Contact for details

Quality Control

Our (17Beta)-3,3-[Ethylenebis(Oxy)]-17-Hydroxyandrost-5-Ene-17-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect the product from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.