Description

1-Methylcyclobutanecarboxylic Acid is a versatile alicyclic carboxylic acid building block of significant interest in advanced organic synthesis. Its unique cyclobutane ring structure imparts valuable steric and electronic properties, making it a critical intermediate for creating novel molecular architectures. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical sectors for the synthesis of active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring constrained, alicyclic frameworks to modulate bioavailability and receptor binding.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where its structure can contribute to improved efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis, enabling the production of enantiomerically pure compounds.
• Material Science Research: Employed in the development of specialty polymers, coatings, and additives where the incorporation of a cyclobutane ring can enhance material properties like thermal stability or rigidity.
• Flavor and Fragrance Chemistry: Acts as a starting material for the synthesis of unique musk and amber odorants, contributing to complex fragrance compositions.
• Chemical Research & Development: A valuable reagent for method development and exploring new chemical spaces in academic and industrial R&D laboratories.

Basic Information

Item	Details
Product Name	1-Methylcyclobutanecarboxylic Acid
CAS No.	32936-76-8
Molecular Formula	C6H10O2
Molecular Weight	114.14 g/mol
Synonyms	1-Methylcyclobutanecarboxylic Acid; 1-Methylcyclobutane-1-carboxylic Acid; Cyclobutanecarboxylic acid, 1-methyl-; 1-Methyl-1-cyclobutanecarboxylic acid; Methylcyclobutanecarboxylic acid; 32936-76-8
EINECS	Contact for details

Quality Control

Our 1-Methylcyclobutanecarboxylic Acid is produced and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.