Description

α-(6-Methoxy-2-Naphthyl)Lactic Acid is a high-purity chiral intermediate featuring a naphthalene core substituted with a methoxy group and a lactic acid side chain. This compound matters as a critical building block in the synthesis of enantiomerically pure pharmaceuticals, where its specific stereochemistry is essential for biological activity. It is primarily needed by research institutions and manufacturers in the pharmaceutical industry developing non-steroidal anti-inflammatory drugs (NSAIDs) and other therapeutic agents.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs).
• NSAID Development: Particularly relevant for the research and production of naproxen and related anti-inflammatory compounds.
• Asymmetric Synthesis: Used as a starting material or resolving agent in chiral synthesis and catalysis.
• Biochemical Research: Serves as a standard or reagent in studies involving enzyme inhibition and receptor binding.
• Fine Chemical Production: Employed in the manufacture of other complex, high-value specialty chemicals.

Basic Information

Product Name	α-(6-Methoxy-2-Naphthyl)Lactic Acid
CAS No.	32721-11-2
Molecular Formula	C₁₄H₁₄O₄
Molecular Weight	246.26 g/mol
Synonyms	2-(6-Methoxy-2-naphthyl)propanoic acid, α-Methyl-6-methoxy-2-naphthaleneacetic acid, (S)-2-(6-Methoxynaphthalen-2-yl)propanoic acid (for specific enantiomer), 6-Methoxy-α-methyl-2-naphthaleneacetic acid, Naproxen impurity, Naproxen related compound, (+)-6-Methoxy-α-methyl-2-naphthaleneacetic acid, DL-2-(6-Methoxy-2-naphthyl)propionic acid
EINECS	Contact for details

Quality Control

Our α-(6-Methoxy-2-Naphthyl)Lactic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (for enantiomerically pure grade)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.