Description

2-Hydroxy-5-Phenylethynyl-Benzoic Acid is a specialized aromatic carboxylic acid derivative featuring a phenylethynyl substituent, which imparts unique electronic and steric properties. This compound serves as a valuable advanced pharmaceutical intermediate (API) and a versatile organic synthesis building block for constructing complex molecular architectures. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for targeted therapies.
• Organic Synthesis Reagent: Used in coupling reactions (e.g., Sonogashira, Suzuki) to introduce conjugated alkyne-aromatic systems.
• Ligand Precursor: Serves as a starting material for synthesizing complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Intermediate in the development of new generation pesticides and herbicides with specific modes of action.
• Material Science: Monomer or additive for creating specialized polymers with tailored optical or electronic properties.
• Chemical Research & Development: A high-purity reference standard for analytical method development and quality control in chemical production.

Basic Information

Product Name	2-Hydroxy-5-Phenylethynyl-Benzoic Acid
CAS No.	32192-74-8
Molecular Formula	C15H10O3
Molecular Weight	238.24 g/mol
Synonyms	5-(Phenylethynyl)salicylic Acid; 2-Hydroxy-5-(phenylethynyl)benzoic Acid; 5-(2-Phenylethynyl)-2-hydroxybenzoic Acid; Benzoic acid, 2-hydroxy-5-(2-phenylethynyl)-; 2-Hydroxy-5-(phenylethinyl)benzoic Acid; 5-Phenylethynylsalicylic Acid; 2-Hydroxy-5-(phenylethynyl)benzoic acid (CAS 32192-74-8)
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-5-Phenylethynyl-Benzoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.