Description

8-Methoxy-1,2,3,4-Tetrahydronaphthalene-2-Carboxylic Acid is a high-purity, functionalized tetralin derivative that serves as a critical chiral building block and advanced pharmaceutical intermediate. Its value lies in its unique structural framework, which is integral to the synthesis of complex molecules with targeted biological activity. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of central nervous system (CNS) active drugs, cardiovascular agents, and other therapeutic compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its tetralin core for biological activity.
• Fine Chemical Building Block: Employed in asymmetric synthesis and medicinal chemistry for constructing complex, polycyclic molecular architectures.
• Research & Development: Serves as a standard or starting material in academic and industrial R&D for method development and biological screening.
• Ligand and Catalyst Precursor: Potential use in the synthesis of chiral ligands for asymmetric catalysis.

Basic Information

Product Name	8-Methoxy-1,2,3,4-Tetrahydronaphthalene-2-Carboxylic Acid
CAS No.	32178-63-5
Molecular Formula	C₁₂H₁₄O₃
Molecular Weight	206.24 g/mol
Synonyms	2-Carboxy-8-methoxy-1,2,3,4-tetrahydronaphthalene; 8-Methoxy-1,2,3,4-tetrahydro-2-naphthoic acid; 8-Methoxy-2-tetralincarboxylic acid; 8-Methoxytetralin-2-carboxylic acid; 2-Naphthalenecarboxylic acid, 1,2,3,4-tetrahydro-8-methoxy-; (RS)-8-Methoxy-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 8-Methoxy-1,2,3,4-Tetrahydronaphthalene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.