Description

p-Toluenesulfonamide, n-(4-Chloro-3-Oxobutyl)- is a specialized organic intermediate featuring a sulfonamide group linked to a reactive chloroketone moiety. This unique bifunctional structure makes it a valuable building block for synthesizing more complex molecules in fine chemical and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for constructing novel chemical entities and developing active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those requiring sulfonamide or specific ketone functionalities.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its reactive chloro and carbonyl groups.
• Fine Chemical Production: Serves as a versatile building block for creating complex dyes, pigments, and functional materials.
• Bioconjugation & Linker Chemistry: The chloroketone group can be utilized for attaching molecules to proteins, polymers, or surfaces in biochemical applications.
• Polymer Modification: Acts as a monomer or cross-linking agent in the development of specialty polymers with tailored properties.
• Academic & Industrial Research: A valuable reagent for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Product Name	p-Toluenesulfonamide, n-(4-Chloro-3-Oxobutyl)-
CAS No.	31984-14-2
Molecular Formula	C11H14ClNO3S
Molecular Weight	275.75 g/mol
Synonyms	4-Chloro-1-(4-methylphenylsulfonyl)-2-butanone; 1-Chloro-4-[(4-methylphenyl)sulfonyl]-2-butanone; N-(4-Chloro-3-oxobutyl)-4-methylbenzenesulfonamide; 4-Methyl-N-(4-chloro-3-oxobutyl)benzenesulfonamide; p-Tolylsulfonyl chlorobutyl ketone; Tosyl chlorobutyl ketone; 4-Chloro-1-tosyl-2-butanone; 31984-14-2
EINECS	Contact for details

Quality Control

Our p-Toluenesulfonamide, n-(4-Chloro-3-Oxobutyl)- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.