Description

(E)-3-Phenyl-1-[(2R)-3,3Aβ,4,5-Tetrahydro-8-Hydroxy-2,5,5-Trimethyl-2α,4α-Ethano-2H-Pyrano[4,3,2-De]-1-Benzopyran-7-Yl]-2-Propen-1-One is a complex, high-purity chroman derivative with a defined stereochemistry. This compound is valued for its role as a key synthetic intermediate and building block in advanced organic synthesis. It is primarily utilized by research institutions and pharmaceutical development companies for the creation of novel chemical entities and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting neurological or metabolic pathways.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex heterocyclic frameworks and studying structure-activity relationships (SAR).
• Chiral Synthesis: The defined (2R) stereocenter makes it a valuable starting material for the preparation of enantiomerically pure compounds.
• Reference Standard: Employed as an analytical standard in method development and quality control for related pharmaceutical processes.
• Material Science Precursor: Potential use in the development of advanced organic materials with specific optical or electronic properties.

Basic Information

Product Name	(E)-3-Phenyl-1-[(2R)-3,3Aβ,4,5-Tetrahydro-8-Hydroxy-2,5,5-Trimethyl-2α,4α-Ethano-2H-Pyrano[4,3,2-De]-1-Benzopyran-7-Yl]-2-Propen-1-One
CAS No.	31759-29-2
Molecular Formula	C26H28O4
Molecular Weight	404.50 g/mol
Synonyms	7-[(1E)-3-Oxo-3-phenylprop-1-en-1-yl]-2,5,5-trimethyl-2,4-ethano-8-hydroxy-3,4,4a,5,6,7-hexahydro-2H-pyrano[4,3,2-de]chromen-3-ol; (2R)-7-[(1E)-3-Oxo-3-phenylprop-1-en-1-yl]-2,5,5-trimethyl-2,4-ethano-8-hydroxy-3,4,4a,5,6,7-hexahydro-2H-pyrano[4,3,2-de]chromen-3-ol; Chroman propenone derivative; CAS 31759-29-2
EINECS	Contact for details

Quality Control

Our (E)-3-Phenyl-1-[(2R)-3,3Aβ,4,5-Tetrahydro-8-Hydroxy-2,5,5-Trimethyl-2α,4α-Ethano-2H-Pyrano[4,3,2-De]-1-Benzopyran-7-Yl]-2-Propen-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis, to ensure high chemical and isomeric purity suitable for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.