Description

Dimethylketene Methyl Trimethylsilyl Acetal is a versatile organosilicon reagent primarily used as a protective agent and a key synthon in advanced organic synthesis. Its value lies in its ability to act as a masked ketene equivalent, facilitating the formation of complex molecular frameworks under mild conditions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate Synthesis: A critical building block for constructing β-lactam rings, a core structure in many antibiotics, and other heterocyclic compounds.
• Agrochemical Development: Used in the synthesis of advanced pesticide and herbicide molecules, leveraging its reactivity to create novel carbon-chain extensions.
• Peptide Modification & Protection: Serves as a trimethylsilyl (TMS) acetal protecting group for carbonyl functionalities during multi-step peptide and complex molecule synthesis.
• Polymer Chemistry: Employed as a monomer or co-monomer precursor in the development of specialized silicon-containing polymers with unique properties.
• Material Science Research: Utilized in surface modification and the creation of advanced organic-inorganic hybrid materials.
• Academic & R&D Laboratories: A valuable tool for methodological development in organic chemistry, particularly in studies involving ketene chemistry and C-C bond formation.

Basic Information

Product Name	Dimethylketene Methyl Trimethylsilyl Acetal
CAS No.	31469-15-5
Molecular Formula	C8H18O2Si
Molecular Weight	174.31 g/mol
Synonyms	1-Methoxy-2-methyl-1-(trimethylsilyloxy)-1-propene; 2-Methoxy-2-methyl-1-(trimethylsiloxy)-1-propene; (1-Methoxy-2-methylprop-1-en-1-yloxy)trimethylsilane; Dimethylketene O-Methyl O-Trimethylsilyl Acetal; Trimethylsilyl Dimethylketene Methyl Acetal; Methyl Trimethylsilyl Dimethylketene Acetal; TMS Dimethylketene Methyl Acetal
EINECS	Contact for details

Quality Control

Our Dimethylketene Methyl Trimethylsilyl Acetal is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at temperatures between 2°C and 8°C (refrigerated) or as specified on the label. Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) to prevent moisture ingress and decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.