Description

[(4-Nitrophenyl)Sulfonyl]Methyl 4-Methylbenzenesulfonate is a specialized sulfonate ester compound that serves as a valuable synthetic intermediate and protecting group reagent in advanced organic synthesis. Its molecular architecture, featuring both a nitro-activated phenylsulfonyl group and a tosylate leaving group, makes it a versatile electrophile for constructing complex molecules. This high-purity chemical is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel drug candidates, particularly those requiring sulfonamide or sulfonate ester functionalities.
• Agrochemical Synthesis: Serves as a key building block in the development of new herbicides, fungicides, and insecticides.
• Polymer & Material Science: Employed in the creation of specialty polymers, functional monomers, and advanced materials with specific surface properties.
• Chemical Research & Development: Acts as a versatile reagent for introducing the (4-nitrophenyl)sulfonyl (Nosyl) protecting group in multi-step synthetic sequences.
• Dye & Pigment Manufacturing: Utilized as a precursor in the synthesis of specialized dyes and colorants.
• Cross-coupling Reactions: Functions as an electrophilic partner in various metal-catalyzed cross-coupling methodologies.

Basic Information

Product Name	[(4-Nitrophenyl)Sulfonyl]Methyl 4-Methylbenzenesulfonate
CAS No.	31081-08-0
Molecular Formula	C14H13NO7S2
Molecular Weight	371.38 g/mol
Synonyms	Nosylmethyl Tosylate; 4-Methylbenzenesulfonic Acid [(4-Nitrophenyl)Sulfonyl]Methyl Ester; p-Toluenesulfonic Acid Nosylmethyl Ester; 1-[(4-Nitrophenyl)Sulfonyl]Methyl 4-Methylbenzenesulfonate; (4-Nitrobenzenesulfonyl)Methyl Tosylate; Nosylmethyl 4-Toluenesulfonate
EINECS	Contact for details

Quality Control

Our production of [(4-Nitrophenyl)Sulfonyl]Methyl 4-Methylbenzenesulfonate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure consistency and reliability. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, guaranteeing the material meets the high standards required for research and commercial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.