Description

[3R-(3Alpha,3Abeta,7Beta,8Aalpha)]-1,2,3,7,8,8A-Hexahydro-3,6,8,8-Tetramethyl-4H-3A,7-Methanoazulen-4-One is a high-purity, complex sesquiterpenoid ketone with a distinctive methanoazulene core structure. This compound is valued for its unique stereochemistry and functional group, making it a critical advanced intermediate in fine chemical synthesis and fragrance research. It is primarily sought by R&D chemists and manufacturers in the flavor & fragrance, pharmaceutical, and specialty chemical industries for developing novel compounds and high-value aroma chemicals.

Application

• Fragrance & Flavor Intermediate: Serves as a key building block for synthesizing complex, woody, and ambery odorants due to its methanoazulene skeleton.
• Pharmaceutical Research: Used as a chiral intermediate or a scaffold in medicinal chemistry for exploring new therapeutic agents.
• Organic Synthesis: Acts as a versatile starting material or intermediate for synthesizing other sesquiterpenoids and natural product analogs.
• Aroma Chemical Production: Employed in the manufacture of high-end specialty aroma chemicals for perfumery applications.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical testing, quality control, and method development in laboratories.

Basic Information

Product Name	[3R-(3Alpha,3Abeta,7Beta,8Aalpha)]-1,2,3,7,8,8A-Hexahydro-3,6,8,8-Tetramethyl-4H-3A,7-Methanoazulen-4-One
CAS No.	30960-39-5
Molecular Formula	C15H22O
Molecular Weight	218.33 g/mol
Synonyms	3R-(-)-Ambrox; (3R,3aS,7R,8aS)-3,6,8,8-Tetramethyloctahydro-1H-3a,7-methanoazulen-4-one; (-)-Ambrox; (3R,5aS,9aS,9bR)-3,6,6,9a-Tetramethyldodecahydronaphtho[2,1-b]furan; 3a,6,6,9a-Tetramethyldodecahydronaphtho[2,1-b]furan; (-)-Ambroxide (related); 3R-(-)-Ambroxan; 1H-3a,7-Methanoazulen-4-ol, octahydro-3,6,8,8-tetramethyl-, [3R-(3.alpha.,3a.beta.,7.beta.,8a.alpha.)]-
EINECS	Contact for details

Quality Control

Our [3R-(3Alpha,3Abeta,7Beta,8Aalpha)]-1,2,3,7,8,8A-Hexahydro-3,6,8,8-Tetramethyl-4H-3A,7-Methanoazulen-4-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and chiral analysis, to ensure identity, purity, and enantiomeric excess meet exacting specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral GC/HPLC)	≥ 99.0% ee
Melting Point	76°C - 80°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.